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£­£­>>¡¡Multi-functional bio-detectors, biological (cells, mitochondria, etc.) characteristics of computer measurement of oxygen analysis system¡¡<<£­£­

I.Preface

epartment of the project and the joint development of the Jishuitan Hospital in Beijing.

II.Functional overview

The use of a variety of biological sensors on the human body, different types of biomass for a 24-hour real-time monitoring, and further the use of computer analysis, forecasting.

Clinical medicine and scientific experiments in the course of the study, the need for the body's temperature, blood pressure, heart rate, PO2, PH2, PCO2, E (G) and many other observations of biomass, the traditional approach is the use of a variety of specialized instruments, meters tools such as the determination of these parameters one by one record. Deficiencies are obvious:

The first is related to the instruments, gauges and other tools and more inconvenient to the management and use; followed by the continuous measurements can not be achieved, can only be selected for some time, limited access to data; Finally, the measurement can not be done under the premise of further statistical , analysis and forecasting.

Multi-functional bio-detector is the traditional method to solve the above-mentioned inadequacies of specially developed using advanced bio-sensing technology, on the human body to carry out a number of parameters measured at the same time, extremely fast, these measurements in real time by computer the collection, processing, storage, and complete the necessary statistics, analysis and forecasting.

III.System structure and working principle

System consists of a variety of sensors, data acquisition equipment and computer components, to facilitate the portability of notebook computer selection. Data acquisition system on the one hand, to connect all the different types of biological sensors, on the other hand, RS-232 output to the computer serial port access.

Applications software is another key to the development of this package is full use of decades of clinical experimental data analysis, the corresponding mathematical model specially designed. Fully taken into account a variety of hospitals and medical research sector, the use of the actual situation.

Biological (cells, mitochondria, etc.) characteristics of computer measurement of oxygen analysis system

1. Features: Characteristics of biological materials is the evaluation of oxygen vitality and function of organisms an important indicator, so in biology, low temperature biology, physiology, pathology, genetics, clinical medicine, pharmacology, nutrition and other fields, how to carry out measurements and analysis, has attracted much public concern and the need to resolve an important issue.
Mitochondria is an important cellular organelle is the place for cell respiration, cell energy needs of the various activities, mainly through the mitochondrial respiration to provide. Studies have shown that mitochondrial ATP synthesis in addition to, but also extremely important with a wide range of cell functions, including generation of reactive oxygen species superoxide anion, redox regulation of cell redox potential and conduction, regulation of apoptosis and gene expression and growth in biological , development, aging, disease, death, and the study of biological evolution, there are important theoretical and practical significance, and thus the current life sciences constitute a new growth point.

"Measurement of biological oxygen characteristics of computer analysis system," the organization may be tablets, organizations at the end of tissue, cells, mitochondria and other characteristics of wood samples to measure oxygen and analytical processing, which can be obtained within a certain period of time the oxygen consumption, oxygen consumption change rate, the efficiency of oxidative phosphorylation, respiratory control ratio, and results.

II. Composition: mainly by the electromagnetic stirrer system, measurement of oxygen tanks, oxygen electrode, the system-specific circuit, constant temperature heating circuits, micro-computers, printers, system-specific software, etc..

III. Characteristics: the system of Biophysics, Chinese Academy of Sciences, the military medical, the medical department of Peking University, Shanghai Second Medical University, Third Military Medical University, Shandong College of Life Sciences, O People's Liberation Army Hospital three years of application and other units, we can see the system has the following salient features:

Test items and more powerful; micro-computer automatic data collection, rapid analysis, and the results stored; compared with manual processing, greatly improving the speed and accuracy of the calculation; to graphic files (the original test curve) and text files ( original data) the form of a large number of experimental data and results stored for at any time to find, retrieve or print output; computer interface clarity can be flexible for a variety of experimental projects and select and set parameters; simple; oxygen electrode design, high sensitivity, dark current small, durable; cost-effective than foreign products.

IV. Principle: Polarographic oxygen electrode is based on principle and made, it is a unique electrochemical gas sensing device, the cathode and anode voltage of the role of a certain polarization, the gas permeable membrane and through the spread of oxygen within the electrolyte resulting electrochemical reaction, the reaction produced a very weak current and the partial pressure of oxygen outside the membrane is proportional to, the weak signal amplification, processing, transformation evacuation analysis of micro-computer processing and computing, data and results into the hard disk. Heating and temperature measuring circuit so that the liquid oxygen tank temperature, electromagnetic stirrer can reduce the pool of liquid temperature gradient.

* Equipment warranty for one year, long-term technical services
* Computer, printer-matching



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